Dr. Kolla Parthasaradhi (MD Ayurveda) describes about the innumerable health benefits of black seed (N. sativa) (Nigella Sativa). He also goes on to say that N.Sativa also called as Kalonji is an essential herb from heaven. Dr. K. Parthsaradhi owns the Partha Ayurvedic Specialty Hospital in Tirupati and is one of the leading most popular doctors in this seven hills temple town known for his impeccable record in spreading good health awareness tips and providing effective treatment for various disorders without any side effects.

N. Sativa (Kalonji) (Black Seed) Good Health Uses | Dr. K. Parthasaradhi (MD Ay) Partha Ayurvedic Hospital, Tirupati
We look in to the various health benefits of this miracle herb N. Sativa. This article is based on one of the articles of Dr Kolla Parthasaradhi (MD Ay), an Ayurvedic doctor based in Tirupari own the Partha Ayurvedic Speciality Hospital.

Medicinal plants have been used for curing diseases for many centuries in different indigenous systems of medicine, the preparation of herbal medicines as they are considered to be safe as compared to allopathic medicines. many researchers are focusing on medicinal plants --- that--- have been thoroughly investigated for their medicinal properties, potential, mechanism of action, safety evaluation and toxicological studies.
Among various medicinal plants, nigella sativa (N.sativa) is emerging as a miracle herb with a rich historical and religious background since many researches revealed its wide spectrum of pharmacological potential. Nigella Sativa has also been described as the miraculous plant and considered by the earliest herbal specialists as ' the herb from heaven'.
N.Sativa is native to southern europe, north africa and south west asia and it is cultivated in many countries in the world like south europe, India, pakistan, syria, turkey, saudi arabia.
Lets take a look at the
Morphology of Plant
N.sativa is an annual flowering plant which grows to 20-90cm tall, with finely divided leaves, the leaf segments narrowly linear to threadlike.
Botanical name : Nigella sativa. Linn.
Family : Apiaceae/Ranunculacae.
Classical Categorization: Kaiyyadeva Nigantu Oshadi varga, Jeerakatraya
Dhanavantari nigantu - Shatapushpadi varga
Names : in different languages
hindi - Kalonji
tamil - karun jeeraka
telugu-nalla jilakarra
English-small fennel
Chemical constituents
This black seed contains fixed and essential oils, proteins, alkaloids, cynine, carvone, thymoquinone - is the major chemical component.
Medicinal properties
Rooksha, Laghu, Rasa-Katu, Vipaka-Katu< Veerya-Ushna
Tridosha effect
Kapha, Vatahara, Pitha vardaka
Parts used
Seed, Seed Oil dose 1-3gr
Oil-3-5 drops
Varieties
there are two herbs used in the name of black cumin
1-> Carum bulbo castanum -Black caraway
2-> Nigella sativa-Small fennel
Benefits
Rochana, Deepana, Vatahara, Samgrahi, Chakshuya, Gulma, Chardi, Atisara hara
The medicinal use of black cumin seeds in various traditional herbal systems is known for (---treating ---) a wide range of ailments which include different airway disorders, for pain such as chronic headache and back pain, diabetes, paralysis, infection, inflammation, hypertension, and digestive tract related problems administered in different kinds of preparation.
** Caution -> Black seed may not be for everyone **
Some studies have found hat kalonji and its components may influence blood clotting. Additionally, while some animal studies have found that kalonji can be safely consumed during pregnancy, one animal study found that the oil could slow down uterine contractions when used in large amounts.
Pharmacological action of black seeds
Nigella sativa has been broadly studied in the last few decades and studies have reported that it possesses a number of medicinal properties and pharmacological actions.
Helps in Weight loss, prevent obesity, Maintain correct BMI : Nigella Sativa

Kalonji contains nigellone, an antioxidant enzyme, which helps in controlling obesity by decreasing (----) appetite, glucose absorption, and gluconeogenesis.
Antioxidant activity : Nigella Sativa

Severak compounds found in kalonji, such as thymoquinone, carvacrol, l-ancthole (----), 4- terpineol, are responsible for its potent anti oxidant properties.
Anti-diabetic activity : Nigella Sativa (black seed/ Kalonji)

According to a study conducted by ICMR (Indian Council of Medical Research) (---), Kalonji was found to be useful in the prevention of diabetes (---) by maintaining the gradients of serum insulin and serum glucose. As compared to the common drug for diabetes i.e. Metformin, black seed is equally efficient in improving glucose tolerance.
The administration of black cumin seed for one month to steptozotocin-induced diabetic rats displayed a significant reduction of fasting plasma glucose, serum MDA, interleukin-6, and immunoglobulin A, G and M, while substantial increment of endogenous anti oxidant enzymes.
Anti-lipidemic activity of N.sativa (Kalonji / Black Seed)

1g/day administration increased high density lipoprotein cholestrol (HDL-c) levels after 3 months while two and three grams per day of N.sativa seed significantly decreased serum levels of total cholesterol (TC) and triglyceride (TG) as well as low-density lipoprotein cholestrol (LDL-c) and increased plasma HDL.
Anti-hypertensive activity of N.sativa (Black seed/Kalonji)

Researches show that patients who were allocated to receive 2 gram daily supplementation of black cumin for one year displayed a noticeable reduction in systolic, diastolic, and mean arterial BP, heart rate.
Neuro-protective Effects of N.sativa (Kalonji/Black seed)

Repeated administration of N.sativa in rats indicated that, there was an improvement in learning and recall status. In addition, flavonoids isolated (----) from black cumin have been shown to modulate critical neuronal signalling paths involved in the processes of memory and are likely to affect synaptic plasticity and long standing potentiating mechanisms.
Anti inflammatory and analgesic effects of N.sativa (Black seed/Kalonji)

*Inflammation has a key role in various medical conditions such as cystic fibrosis, rheumatoid arthritis, osteoarthritis, asthma, allergies and cancer which all are associated with acute and chronic pain.
*The volatile oil of black cumin and thymoquinone at various doses revealed a dose reliant anti-inflammatory activity. The volatile oil of N.sativa seed also displayed a substantial pain relieving effect.
*Black cumin extract caused substantial rises in entirely measured respiratory function tests and the starting time of bronchodilator action of the extract was comparable to that of theophylline.
*The efficacy of of black cumin oil in patients with rheumatoid arthritis (RA) (---), noticeable improvement was displayed in number of inflamed joints, incidence of morning stiffness. and disease activity after the consumption of black cumin.
Antimicrobial, Antifungal, Antiparasitic, Antiviral activity of N.sativa (Kalonji/Black Seed)

Among the inspiring medicinal plants, black cumin is the one that displayed strong antibacterial, antiviral, antifungal and anti parasitic actions.
Thymoquinone obtained from seeds of N.sativa revealed broader spectrum activities against multiple strains of gram positive and gram negative bacteria, including Bacillus and powerful antifungal activity.
Anti-cancer Activity of N.sativa (Kalonji/Black Seed) and reducing chemotherapy side effects

According to reports, decrease in tumor cells have been observed due to restrict (--- ing) the proliferation of cancer cells by Apoptosis induction, reactive oxygen, anti-proliferation, anti metastasis, anti-angiogenesis. Thymoquene when administered with chemotherapeutic drugs have positive impact on cancer (---treatment) reduce the toxicity of chemo therapy. The extensive researches using modern scientific techniques were carried out by various researchers on n.sativa since it is believed to be a miraculous herb that can cure multiple ailments and disorders.
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